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If you drink lactose free milk, you are drinking milk from a transgenic cow that was engineered to produce less lactose in their milk.
The ability to change an organism's genome is very controversial, especially when it comes to the impact it has on human beings.
Genetic manipulation is, in essence, a process done to manipulate the genome of an organism in order to produce desired traits.
Think of creating a modified gene as a super fancy kindergarten collage project; you will need scissors and glue.
Restriction enzymes are like molecular scissors that can cut DNA.